Organic Acids
Medchemexpress LLC IIQLPEIVVV TFA | 99.9% | 1122.40 | 1 MG
IIQLPEIVVV TFA is a specific inhibitor of Drp1-Mff interaction. It can distinguish physiological from pathological fission and block physiological fission, leading to mitochondrial dysfunction. It can be used in the study of Huntington's disease.
- Specific inhibitor of Drp1-Mff interaction
- Distinguishes physiological from pathological fission
- Blocks physiological fission
- Leads to mitochondrial dysfunction
- Used in the study of Huntington's disease
- Purity of 99.91%
- White to off-white solid appearance
- Sequence: Ile-Ile-Gln-Leu-Pro-Glu-Ile-Val-Val-Val
Medchemexpress LLC c(avb6)-DOTA TFA | 98.6% | 1546.65 | 1 MG
c(avb6)-DOTA TFA is a conjugate of the αvβ6 integrin selective peptide ring modified with the DOTA chelator. The Lu(III) complex of c(avb6)-DOTA TFA shows a comparable affinity for αvβ6 integrin (IC50=0.8 nM) and can be utilized as a tumor diagnostic.
- Conjugate of αvβ6 integrin selective peptide ring
- Modified with DOTA chelator
- Lu(III) complex shows comparable affinity for αvβ6 integrin (IC50=0.8 nM)
- Can be utilized as a tumor diagnostic
- Intended for research use only
Medchemexpress LLC 2-Furancarboxamide, 5-nitro-N-[4-[7-(1,2,3,6-tetrahydro-4-pyridinyl)imidazo[1,2-a]pyridin-3-yl]phenyl] | C25H20F3N5O6 | 5 MG
W1131 TFA is a potent STAT3 inhibitor that induces ferroptosis. It inhibits cancer progression in subcutaneous xenograft, organoid, and PDX models of gastric cancer. W1131 effectively alleviates cancer cell chemoresistance to 5-FU, and regulates the cell cycle, DNA damage response, and oxidative phosphorylation, including the IL6-JAK-STAT3 pathway and the ferroptosis pathway.
- Potent STAT3 inhibitor
- Induces ferroptosis
- Inhibits cancer progression in gastric cancer models
- Alleviates cancer cell chemoresistance to 5-FU
- Regulates cell cycle and DNA damage response
- Regulates oxidative phosphorylation
- Regulates IL6-JAK-STAT3 pathway
- Regulates ferroptosis pathway
Medchemexpress LLC TL033 | 2356230-22-1 | 1630.83 | 25 MG
TL033 is a chemical substance identified for laboratory use, including the manufacture of other substances. It is supplied as a solid and is intended for research purposes only by experienced personnel.
- Identified for laboratory chemical manufacturing
- Supplied as a solid
- Recommended storage at -20°C, protected from light
- Stable under recommended storage conditions
- For research use only
Medchemexpress LLC NN1177 (TFA) | 98.7% | 4570.07 (free base) | 25 MG
NN1177 TFA is a long-acting GLP-1/glucagon receptor co-agonist. It induces dose-dependent body weight loss in diet-induced obese mice. This product is for research use only.
- Long-acting GLP-1/glucagon receptor co-agonist
- Induces dose-dependent body weight loss in diet-induced obese mice
- Reduces CYP3A4 mRNA expression and activity in human hepatocytes
- Improves glucose tolerance in diet-induced obese mice
- Reduces liver fat and inflammatory biomarkers in NASH model mice
Medchemexpress LLC YKL-5-124 trifluoroacetate | 2748220-93-9 | 99.7% | 629.63 | C30H34F3N7O5 | 10 MM x 1 ML
YKL-5-124 TFA is the trifluoroacetate salt of a potent, selective, irreversible, covalent cyclin-dependent kinase 7 (CDK7) inhibitor. Supplied as a 10 mM solution in DMSO (1 mL), it is intended for research use in biochemical and cellular assays and is reported to induce cell-cycle arrest and inhibit E2F-driven gene expression while minimally affecting RNA polymerase II phosphorylation.
- Potent, selective CDK7 inhibition
- Irreversible covalent mechanism of action
- Supplied as a 10 mM solution in DMSO, 1 mL vial
- High purity suitable for biochemical and cellular studies
- Molecular formula and mass provided for identification
Medchemexpress LLC Lysylcysteine TFA | 97.8% | 477.38 | 25 MG
Lysylcysteine TFA (L-Lysyl-L-cysteine TFA) is a dipeptide composed of lysine and cysteine, intended for research use only. It is not for human use. This product is provided as a white to off-white solid with a high purity of 97.84% and a molecular weight of 477.38. It is shipped at room temperature in the continental US and requires sealed storage away from moisture.
- High purity: 97.84%
- Molecular weight: 477.38
- Dipeptide composed of lysine and cysteine
- Appearance: White to off-white solid
- Sequence: Lys-Cys
- Storage for powder: -80°C for 2 years, -20°C for 1 year
- Storage in solvent: -80°C for 6 months, -20°C for 1 month
![eMolecules 1810069-99-8 | bis(2,2,2-trifluoroacetic acid);2-(2,2,2-trifluoroethyl)-2,6-diazaspiro[3.3]heptane | MFCD29037458 | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502158414.JPG-250.jpg)
eMolecules 1810069-99-8 | bis(2,2,2-trifluoroacetic acid);2-(2,2,2-trifluoroethyl)-2,6-diazaspiro[3.3]heptane | MFCD29037458 | 1g
Medchem Express | Azosemide | 10mg | 495799592 | HY-107321 | 27589-33-9 | MFCD00867321 | 370.830 | C12H11ClN6O2S2
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Medchemexpress LLC Larllt tfa | 99.9% | 799.88 | 25 MG
LARLLT TFA is an EGFR-binding peptide with potential for research into EGFR overexpressing cancers. This peptide is suitable for studies involving lung, ovarian, and colorectal cancer.
- EGFR-binding peptide
- Potential for research into EGFR overexpressing cancers
- Suitable for lung, ovarian, and colorectal cancer studies
Medchemexpress LLC Maurocalcine TFA | 269745-22-4 | 95.09% | 3858.55 (free base) | 1 MG
Maurocalcine TFA is an agonist of ryanodine receptor (RyR) channel types 1, 2, and 3 with cellular permeability. It induces [3H]ryanodine binding on RyR1 with an EC50 value of 2558 nM and exhibits an apparent affinity of 14 nM for RyR2. This compound can be applied to in vivo cell tracking or other cell imaging techniques. Maurocalcine (100 nM, 24 h) increases the sensitivity of RyR2 to activating [Ca2+]i and decreases its sensitivity to inhibiting [Ca2+]i. Maurocalcine (5 μM, 4 h/24 h) shows no significant cell toxicity for HEK293.
- Agonist of ryanodine receptor (RyR) channel types 1, 2 and 3.
- Possesses cellular permeability.
- Induces [3H]ryanodine binding on RyR1.
- Exhibits affinity for RyR2.
- Can be used for in vivo cell tracking or cell imaging techniques.
Medchemexpress LLC TL033 TFA | 2746343-70-2 | 98.1% | 1630.83 | 5 MG
TL033 TFA (HY-147340A) is a chemical compound with CAS number 2746343-70-2 and a molecular weight of 1630.83. This product is supplied as a light yellow to yellow solid with a high purity of 98.1% (HPLC). It requires specific storage conditions to maintain its integrity, ensuring reliability for research applications.
- CAS number: 2746343-70-2
- Purity (HPLC): 98.1%
- Molecular weight: 1630.83
- Appearance: Light yellow to yellow solid
- Recommended storage (solid): -20°C, sealed, away from moisture and light
- Storage in solvent: -80°C (6 months) or -20°C (1 month), sealed, away from moisture and light
Medchemexpress LLC Imperatoxin A TFA | 98.7% | 3758.35 (free base) | 1 MG
Imperatoxin A TFA is a peptide toxin derived from the venom of the African scorpion Pandinus imperator. It acts as a Ca2+-release channels/ryanodine receptors (RyRs) activator, enhancing the influx of Ca2+ from the sarcoplasmic reticulum into the cell.
- Purity of 98.65%
- Molecular weight of 3758.35 (free base)
- Appearance as a white to off-white solid
- Soluble in H2O at ≥ 100 mg/mL
Medchemexpress LLC Thymocartin TFA 5mg | 5MG
Thymocartin TFA is the TFA salt form of Thymocartin (HY-105025) Thymocartin TFA inhibits apoptosis of peripheral blood lymphocytes in HIV infected individuals Thymocartin TFA is potential for immunodeficiency diseases research[1 [2
Medchemexpress LLC Dendrotoxin-I TFA | 99.9% | 7149.24 | 500 UG
Dendrotoxin-I TFA is a potent K+ channel blocker effective against voltage-gated potassium channel subunits KV1.1, KV1.2, and KV1.6, with IC50s ranging from 0.13-50 nM. This neurotoxin holds potential in cancer research, as demonstrated by its significant tumor growth inhibition effect when combined with hyperthermia in nude mice with MCF-7 cells.
- Potent K+ channel blocker
- Effective against voltage-gated potassium channel subunits KV1.1, KV1.2, and KV1.6
- Exhibits neurotoxic properties
- Potential for use in cancer research
- Demonstrated tumor growth inhibition in in vivo studies